Mephisto
Mephisto has the highest personal damage reduction in the game at 40%, but only while above 70% health. Her buff favors high-defense allies instead of damage dealers.
What she does
Ranked for the global build
Why she ranks here
Mephisto has the highest personal damage reduction in the game at 40%, but only while above 70% health. Her buff favors high-defense allies instead of damage dealers.
Debuff, Earth
B tier in practice
Early fillers
Use them to cover a gap in the first week, then replace them when you can.
When to use her
Use her only as a stopgap tank until you build a stronger Preservation unit.
How to build her
Role-level guidance, not datamined multipliers. The role decides what she needs before any single character quirk does.
Building a Debuff
Stack effect damage and keep the status applied. She needs a fight long enough for Burn, Poison, or Fracture to tick.
Applies Poison, Burn, or other status effects and turns them into damage.
What to build first
Damage reduction first. The team survives because of the cut, not the health bar.
Based on the tags above and on her role. This site does not datamine skill multipliers, so read this as a priority order, not a skill tree. · Self DR
Phase matchup
Earth: Strong against Water, weak against Wind.
Exposed to: Wind
Should you build her?
Build her to cover a gap this week, then replace her.
0 teams use her, 0 list her as a substitute
Who she wants around her
The teams that use her, the teams that list her as a substitute, and the partners her role needs.
No team on the team page uses her yet
No team on the team page uses her yet. Start from the five-slot frame and put her where her role fits.
Partners her role needs
The strongest characters in the roles her job depends on.
Amaterasu
SSS · Tank, Radiant Star
The strongest tank in the global build. Amaterasu heals herself, revives once, and turns Charm into crowd control plus a damage cut for the whole team.
Medusa
SSS · Support, Radiant Star
The best healer in the game. Medusa revives each ally after their first defeat, keeps the team topped up, and adds 30% damage reduction.
Aether
SS · Support, Radiant Star
A healer who also deals damage. Aether gives 25% attack to your two highest-attack allies and cuts energy damage by 40%.
Athena
SS · Tank, Earth
A tank with shields, 30% damage reduction for the team, and a heal block for enemies. Athena protects and disrupts in the same slot.
Who to use instead
The closest swaps in the same role, within one tier step.
Garuda
B · Debuff, Earth
Garuda applies attack down and defense down, but both effects are chance-based.
Kaguya
B · Debuff, Water
Kaguya needs a Poison team to scale, and even then her damage ceiling is low.
Aries
A · Debuff, Water
Aries is the Poison version of Nezha. She needs a Poison team to reach her damage, but she pays off when the stacks are there.
Ginchiyo
A · Debuff, Wind
Ginchiyo steals attack and defense from enemies, then shares those stats with allies by row. She gets stronger as the fight goes on.
Every character in her role
The whole role in tier order, so a swap is a comparison instead of a guess.
| Character | Tier | Phase | Tags |
|---|---|---|---|
| Izanami | SS | Radiant Star | Burn stacking / Burn amp |
| Pilgrim | SS | Radiant Star | Anti-heal / Poison / Burn |
| Azure | S | Water | Debuff follow-up |
| Lilith | S | Radiant Star | Back-row buff |
| Aries | A | Water | AOE poison / Poison payoff |
| Ginchiyo | A | Wind | Stat steal / Buff sharing |
| Ishtar | A | Earth | Cooldown reset / Scaling |
| Luna | A | Water | Poison / DEF down / DMG down |
| Nezha | A | Fire | AOE burn / Guaranteed crit |
| Garuda | B | Earth | ATK down / DEF down |
| Kaguya | B | Water | Poison synergy |
| MephistoThis page | B | Earth | Self DR / DEF buff |
| Phoenix Flame | C | Fire | Column poison |
| Selina | C | Fire | Row damage |
| Sylph | C | Wind | Fracture / ATK buff |
The phase that beats her
An element matchup decides more fights than a single tier step does.
Exposed to
Wind
Phase matchup
Earth: Strong against Water, weak against Wind.